| The following
information is a summary about Zyban. It is
not intended to replace a doctor's instructions.
(BUPROPION sustained release
- ORAL)
USES
Zyban is used to help you quit smoking.
DIRECTIONS
Swallow this medication whole. Do not crush
or chew them or the sustained activity of the
drug will be destroyed and the chances of side
effects occurring may be increased. Take as
directed, usually twice daily for 7 to 12 weeks.
Do not take more or less medication than prescribed.
Since this drug can cause sleeplessness at first,
it is best not to take near bedtime. It is advised
to continue smoking for the first week after
starting this drug until it reaches higher levels
in your blood. Do not smoke if using any nicotine
products with this drug. Too much nicotine can
cause serious side effects.
PRECAUTIONS
Before taking Zyban tell your doctor if you
have a history of seizures, head injury, brain
tumor; heart, liver or kidney disease, an eating
disorder or any mental conditions, diabetes
or if you have any allergies. Limit or avoid
consumption of alcoholic beverages; alcohol
can increase your risk of seizures. Chronic
alcohol users who suddenly stop the intake of
alcohol while taking bupropion may increase
the risk of having seizures. Suddenly stopping
certain tranquilizers (e.g., diazepam, chlordiazepoxide)
is not recommended because doing so may increase
the risk of having seizures. Elderly patients
may be more sensitive to the effects of this
drug. Tell your doctor if you are pregnant or
plan to become pregnant before taking it. Zyban
is excreted into breast milk. Because of the
potential risk to the infant, BREAST-FEEDING
WHILE USING THIS DRUG IS NOT RECOMMENDED. Consult
your doctor before breast-feeding.
SIDE EFFECTS
This medication is generally well tolerated.
Dry mouth, headache, increased sweating, constipation,
anxiety and fatigue may occur. If these effects
persist or worsen, notify your doctor.
MISSED
DOSE
Take any missed dose as soon as possible but
not if it is within 8 hours of the next dose.
If it is time for the next dose, skip the missed
dose and resume your regular schedule. Do not
"double up" the dose.
DRUG INTERACTIONS
Before taking Zyban tell your doctor of all
nonprescription and prescription medications
you may use especially MAO inhibitors (e.g.,
isocarboxazid, phenelzine, tranylcypromine,
pargyline, selegiline, furazolidone), levodopa,
theophylline, corticosteroids (e.g., prednisone),
seizure medications, sedatives, ritonavir, tranquilizers/psychiatric
drugs (e.g., chlorpromazine), other antidepressants
(e.g., amitriptyline), salicylates (e.g., aspirin,
salsalate), isoniazid, chlolinesterase inhibitors
(e.g., tacrine, donepezil), morphine, and adrenaline-like
drugs (e.g., pseudoephedrine). Excess caffeine
intake can increase the chance of seizures with
this drug. Check all nonprescription/prescription
drug labels for caffeine. Consult doctor or
pharmacist. A certain product used to help quit
smoking contains bupropion. Do not take that
product while using this one.
NOTES
Do not allow anyone else to take Zyban.
STORAGE
Store at room temperature and keep away from
moisture and sunlight. KEEP ZYBAN AND ALL MEDICATIONS
OUT OF THE REACH OF CHILDREN.
For more information on Zyban,
you can visit http://www.zyban.com/
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